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1

Ancient DNA analysis – An established technique in charting the evolution of tuberculosis and leprosy

Donoghue, Helen D., Spigelman, Mark, O'Grady, Justin, Szikossy, Ildikó, Pap, Ildikó, Lee, Oona Y.-C., Wu, Houdini H.T., Besra, Gurdyal S., Minnikin, David E.

Journal:

Year:

2015

Language:

english

File:

PDF, 260 KB

english, 2015

2

Lipid domains of mycobacteria studied with fluorescent molecular probes

Henriette Christensen, Natalie J. Garton, Richard W. Horobin, David E. Minnikin, Michael R. Barer

Journal:

Molecular Microbiology

Year:

1999

Language:

english

File:

PDF, 728 KB

english, 1999

3

Synthesis of (R,S)-10-methyloctadecanoic acid (tuberculostearic acid) and key chiral 2-methyl branched intermediates

Paul A. Wallace, David E. Minnikin, Katharine McCrudden, Andrea Pizzarello

Journal:

Chemistry and Physics of Lipids

Year:

1994

Language:

english

File:

PDF, 1.30 MB

english, 1994

4

Biomolecular archaeology of ancient tuberculosis: response to “Deficiencies and challenges in the study of ancient tuberculosis DNA” by Wilbur et al. (2009)

Helen D. Donoghue, Israel Hershkovitz, David E. Minnikin, Gurdyal S. Besra, Oona Y.-C. Lee, Ehud Galili, Charles L. Greenblatt, Eshetu Lemma, Mark Spigelman, Gila Kahila Bar-Gal

Journal:

Journal of Archaeological Science

Year:

2009

Language:

english

File:

PDF, 201 KB

english, 2009

5

Essentials in the use of mycolic acid biomarkers for tuberculosis detection: response to “High-throughput mass spectrometric analysis of 1400-year-old mycolic acids as biomarkers for ancient tuberculosis infection” by

David E. Minnikin, Oona Y.-C. Lee, Mark Pitts, Mark S. Baird, Gurdyal S. Besra

Journal:

Journal of Archaeological Science

Year:

2010

Language:

english

File:

PDF, 389 KB

english, 2010

6

Ancient mycobacterial lipids: Key reference biomarkers in charting the evolution of tuberculosis

Minnikin, David E., Lee, Oona Y.-C., Wu, Houdini H.T., Besra, Gurdyal S., Bhatt, Apoorva, Nataraj, Vijayashankar, Rothschild, Bruce M., Spigelman, Mark, Donoghue, Helen D.

Journal:

Year:

2015

Language:

english

File:

PDF, 894 KB

english, 2015

7

Lipid biomarkers provide evolutionary signposts for the oldest known cases of tuberculosis

Lee, Oona Y-C., Wu, Houdini H.T., Besra, Gurdyal S., Rothschild, Bruce M., Spigelman, Mark, Hershkovitz, Israel, Bar-Gal, Gila Kahila, Donoghue, Helen D., Minnikin, David E.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.03 MB

english, 2015

8

Human tuberculosis predates domestication in ancient Syria

Baker, Oussama, Lee, Oona Y.-C., Wu, Houdini H.T., Besra, Gurdyal S., Minnikin, David E., Llewellyn, Gareth, Williams, Christopher M., Maixner, Frank, O'Sullivan, Niall, Zink, Albert, Chamel, Bérénice

Journal:

Year:

2015

Language:

english

File:

PDF, 2.00 MB

english, 2015

9

Metagenomic Analysis of Tuberculosis in a Mummy

Chan, Jacqueline Z.-M., Sergeant, Martin J., Lee, Oona Y.-C., Minnikin, David E., Besra, Gurdyal S., Pap, Ilidkó, Spigelman, Mark, Donoghue, Helen D., Pallen, Mark J.

Journal:

Boston Medical and Surgical Journal

Year:

2013

Language:

english

File:

PDF, 427 KB

english, 2013

10

The challenge of identifying tuberculosis proteins in archaeological tissues

Hendy, Jessica, Collins, Matthew, Teoh, Kai Yik, Ashford, David A., Thomas-Oates, Jane, Donoghue, Helen D., Pap, Ildikó, Minnikin, David E., Spigelman, Mark, Buckley, Mike

Journal:

Journal of Archaeological Science

Year:

2016

Language:

english

File:

PDF, 813 KB

english, 2016

11

Recognising the broad array of approaches available for the diagnosis of ancient tuberculosis: Comment on ‘Infectious diseases and Neolithic transformations’ (Fuchs et al. 2019 The Holocene 29: 1545–1557)

Minnikin, David E, Lee, Oona Y-C, Wu, Houdini HT, Besra, Gurdyal S, Donoghue, Helen D

Journal:

Year:

2020

Language:

english

File:

PDF, 301 KB

english, 2020

12

ChemInform Abstract: The Synthesis of Both Enantiomers of Lactobacillic Acid (I) and Mycolic Acid Analogues (II).

Geoffrey D. Coxon, Stefan Knobl, Evan Roberts, Mark S. Baird, Juma R. Al Dulayymi, Gurdyal S. Besra, Patrick J. Brennan, David E. Minnikin

Journal:

Year:

1999

File:

PDF, 26 KB

1999

13

Biphenyl-Based Analogues of Thiolactomycin, Active Against Mycobacterium tuberculosis mtFabH Fatty Acid Condensing Enzyme.

Suzanne J. Senior, Petr A. Illarionov, Sudagar S. Gurcha, Ian B. Campbell, Merrill L. Schaeffer, David E. Minnikin, Gurdyal S. Besra

Journal:

Year:

2004

File:

PDF, 91 KB

2004

14

Acetylene-Based Analogues of Thiolactomycin, Active Against Mycobacterium tuberculosis mtFabH Fatty Acid Condensing Enzyme.

Suzanne J. Senior, Petr A. Illarionov, Sudagar S. Gurcha, Ian B. Campbell, Merrill L. Schaeffer, David E. Minnikin, Gurdyal S. Besra

Journal:

Year:

2004

File:

PDF, 95 KB

2004

15

Synthesis of 4,6:2′,3′:4′,6′-tri-O-cyclohexylidene-α,α′-trehalose 2-palmitate: an intermediate for the synthesis of mycobacterial 2,3

Paul A. Wallace, David E. Minnikin

Journal:

Carbohydrate Research

Year:

1994

Language:

english

File:

PDF, 1.46 MB

english, 1994

16

Synthesis of methyl (Z)-tetracos-5-enoate and both enantiomers of ethyl (E)-6-methyltetracos-4-enoate: possible intermediates in the biosynthesis of mycolic acids in mycobacteria

Gurdyal S. Besra, David E. Minnikin, Paul R. Wheeler, Colin Ratledge

Journal:

Chemistry and Physics of Lipids

Year:

1993

Language:

english

File:

PDF, 827 KB

english, 1993

17

Synthesis of racemic 2,4-dimethyltetradecanoic acid from Mycobacterium kansasii

Paul A. Wallace, David E. Minnikin

Journal:

Chemistry and Physics of Lipids

Year:

1996

Language:

english

File:

PDF, 391 KB

english, 1996

18

Differential conformational behaviors of -mycolic acids in Langmuir monolayers and computer simulations

Masumi Villeneuve, Mizuo Kawai, Motoko Watanabe, Yutaka Aoyagi, Yukio Hitotsuyanagi, Koichi Takeya, Hiroaki Gouda, Shuichi Hirono, David E. Minnikin, Hiroo Nakahara

Journal:

Chemistry and Physics of Lipids

Year:

2010

Language:

english

File:

PDF, 1.08 MB

english, 2010

19

Acetylene-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme

Suzanne J. Senior, Petr A. Illarionov, Sudagar S. Gurcha, Ian B. Campbell, Merrill L. Schaeffer, David E. Minnikin, Gurdyal S. Besra

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 153 KB

english, 2004

20

Adjuvant properties of a simplified C32 monomycolyl glycerol analogue

Veemal Bhowruth, David E. Minnikin, Else Marie Agger, Peter Andersen, Vincent W. Bramwell, Yvonne Perrie, Gurdyal S. Besra

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 274 KB

english, 2009

21

Loss of a Mycobacterial Gene Encoding a Reductase Leads to an Altered Cell Wall Containing β-oxo- Mycolic Acid Analogs and Accumulation of Ketones

Apoorva Bhatt, Alistair K. Brown, Albel Singh, David E. Minnikin, Gurdyal S. Besra

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 1013 KB

english, 2008

22

Synthesis and properties of methyl 5-(1′R,2′S)-(2-octadecylcycloprop-1-yl)pentanoate and other ω-19 chiral cyclopropane fatty acids and esters related to mycobacterial mycolic acids

Geoffrey D Coxon, Juma’a R Al Dulayymi, Caroline Morehouse, Patrick J Brennan, Gurdyal S Besra, Mark S Baird, David E Minnikin

Journal:

Chemistry and Physics of Lipids

Year:

2004

Language:

english

File:

PDF, 152 KB

english, 2004

23

The synthesis of single enantiomers of meromycolic acids from mycobacterial wax esters

Juma'a R. Al Dulayymi, Mark S. Baird, Evan Roberts, David E. Minnikin

Journal:

Year:

2006

Language:

english

File:

PDF, 499 KB

english, 2006

24

Facile synthesis of (Z)-tetracos-5-enoic acid and racemic cis-4-(2-octadecylcyclopropane-1-yl)-butanoic acid

Geoffrey D. Coxon, James D. Douglas, David E. Minnikin

Journal:

Chemistry and Physics of Lipids

Year:

2003

Language:

english

File:

PDF, 68 KB

english, 2003

25

The synthesis of both enantiomers of lactobacillic acid and mycolic acid analogues

Geoffrey D. Coxon, Stefan Knobl, Evan Roberts, Mark S. Baird, Juma R. Al Dulayymi, Gurdyal S. Besra, Patrick J. Brennan, David E. Minnikin

Journal:

Tetrahedron Letters

Year:

1999

Language:

english

File:

PDF, 219 KB

english, 1999

26

The synthesis of (11R,12S)-lactobacillic acid and its enantiomer

Geoffrey D. Coxon, Juma R. Al-Dulayymi, Mark S. Baird, Stefan Knobl, Evan Roberts, David E. Minnikin

Journal:

Tetrahedron: Asymmetry

Year:

2003

Language:

english

File:

PDF, 341 KB

english, 2003

27

The Methyl-Branched Fortifications of Mycobacterium tuberculosis

David E Minnikin, Laurent Kremer, Lynn G Dover, Gurdyal S Besra

Journal:

Chemistry & Biology

Year:

2002

Language:

english

File:

PDF, 405 KB

english, 2002

28

Mycolic acid patterns of some species ofMycobacterium

David E. Minnikin, S. Megan Minnikin, James H. Parlett, Michael Goodfellow, Mogens Magnusson

Journal:

Archives of Microbiology

Year:

1984

Language:

english

File:

PDF, 1.35 MB

english, 1984

29

Lipids in the classification ofNocardioides: Reclassification ofArthrobacter simplex(Jensen) lochhead in the genusNocardioides(Prauser) emend. O'Donnell et al. asNocardioides simplexcomb. nov.

Anthony G. O'Donnell, Michael Goodfellow, David E. Minnikin

Journal:

Archives of Microbiology

Year:

1982

Language:

english

File:

PDF, 1.40 MB

english, 1982

30

Numerical and chemical classification ofStreptosporangiumand some related actinomycetes

Timothy S. Whitham, Medha Athalye, David E. Minnikin, Michael Goodfellow

Journal:

Antonie van Leeuwenhoek

Year:

1993-1994

Language:

english

File:

PDF, 2.26 MB

english, 1993-1994

31

The synthesis of methyl 4-(2-octadecylcyclopropen-l-yl)butanoate: a possible inhibitor in mycolic acid biosynthesis

Gurdyal S. Besra, David E. Minnikin, Michael J. Simpson, Mark S. Baird, Paul R. Wheeler, Colin Ratledge

Journal:

Chemistry and Physics of Lipids

Year:

1993

Language:

english

File:

PDF, 411 KB

english, 1993

32

Synthesis of (2R; 4R,S)- and (2S; 4R,S)-dimethyldocosanoic acids

Paul A. Wallace, David E. Minnikin

Journal:

Chemistry and Physics of Lipids

Year:

1994

Language:

english

File:

PDF, 1.06 MB

english, 1994

33

Synthesis of a derivative of racemic 3-hydroxy-2,4,6-trimethyltetracosanoic (mycolipanolic) acid and racemic 2,4,6-trimethyltetracos-2-enoic (mycolipenic) acid

Paul A. Wallace, David E. Minnikin

Journal:

Chemistry and Physics of Lipids

Year:

1996

Language:

english

File:

PDF, 531 KB

english, 1996

34

Biphenyl-Based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme

Suzanne J Senior, Petr A Illarionov, Sudagar S Gurcha, Ian B Campbell, Merrill L Schaeffer, David E Minnikin, Gurdyal S Besra

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 151 KB

english, 2003

35

Symmetrical and unsymmetrical analogues of isoxyl; active agents against Mycobacterium tuberculosis

Veemal Bhowruth, Alistair K. Brown, Robert C. Reynolds, Geoffrey D. Coxon, Simon P. Mackay, David E. Minnikin, Gurdyal S. Besra

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

36

Identification and structural characterization of an unusual mycobacterial monomeromycolyl-diacylglycerol

Laurent Kremer, Chantal De Chastellier, Gary Dobson, Kevin J. C. Gibson, Pablo Bifani, Stéphanie Balor, Jean-Pierre Gorvel, Camille Locht, David E. Minnikin, Gurdyal S. Besra

Journal:

Molecular Microbiology

Year:

2005

Language:

english

File:

PDF, 549 KB

english, 2005

37

Polar lipid composition in the classification of Arthrobacter and Microbacterium

Matthew D. Collins, Michael Goodfellow, David E. Minnikin

Journal:

FEMS Microbiology Letters

Year:

1982

Language:

english

File:

PDF, 903 KB

english, 1982

38

Direct detection of Mycobacterium tuberculosis lipid antigens by thin-layer chromatography

David E. Minnikin, Malin Ridell, James H. Parlett, Robert C. Bolton

Journal:

FEMS Microbiology Letters

Year:

1987

Language:

english

File:

PDF, 329 KB

english, 1987

39

Characteristic new members of the phthiocerol and phenolphtiocerol families from Mycarbacterium ulcerans

Gurdyal S. Besra, David E. Minnikin, Amin Sharif, John L. Stanford

Journal:

FEMS Microbiology Letters

Year:

1990

Language:

english

File:

PDF, 149 KB

english, 1990

40

Recognition of novel glycolipid antigens from smooth variants of Mycobacterium tuberculosis

David E. Minnikin, Malin Ridell, Robert C. Bolton, Mogens Magnusson

Journal:

FEMS Microbiology Letters

Year:

1990

Language:

english

File:

PDF, 151 KB

english, 1990

41

Ring location in cyclopropane fatty acid esters by boron trifluoride-catalyzed methoxylation followed by mass spectroscopy

David E. Minnikin

Journal:

Year:

1972

Language:

english

File:

PDF, 422 KB

english, 1972

42

Mycocerosic acid biomarkers for the diagnosis of tuberculosis in the Coimbra Skeletal Collection

Janet E. Redman, Matthew J. Shaw, Anthony I. Mallet, Ana Luisa Santos, Charlotte A. Roberts, Angela M. Gernaey, David E. Minnikin

Journal:

Year:

2009

Language:

english

File:

PDF, 762 KB

english, 2009

43

Structures of Phenolic Glycolipids from Mycobacterium Kansasii

Motoko Watanabe, Yutaka Aoyagi, Akihiro Ohta, David E. Minnikin

Journal:

Year:

1997

Language:

english

File:

PDF, 553 KB

english, 1997

44

The interrelation of polar lipids in bacterial membranes

David E. Minnikin, Houshang Abdolrahimzadeh, James Baddiley

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1971

Language:

english

File:

PDF, 278 KB

english, 1971

45

The oxygenated mycolic acids of Mycobacterium fortuitum, M. Farcinogenes and M. Senegalense

David E. Minnikin, S.Megan Minnikin, Michael Goodfellow

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1982

Language:

english

File:

PDF, 661 KB

english, 1982

46

Characterisation of phenolic glycolipids from Mycobacterium marinum

Gary Dobson, David E. Minnikin, Gurdyal S. Besra, Anthony I. Mallet, Mogens Magnusson

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1990

Language:

english

File:

PDF, 716 KB

english, 1990

47

A new glycolipid from Mycobacterium avium—Mycobacterium intracellulare complex

Motoko Watanabe, Sukeyoshi Kudoh, Yasuji Yamada, Kazuo Iguchi, David E. Minnikin

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1992

Language:

english

File:

PDF, 1.01 MB

english, 1992

48

Stimulation of mycolic acid biosynthesis by incorporation of cis-tetracos-5-enoic acid in a cell-wall preparation from Mycobacterium smegmatis

Paul R. Wheeler, Gurdyal S. Besra, David E. Minnikin, Colin Ratledge

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1993

Language:

english

File:

PDF, 840 KB

english, 1993

49

Structural elucidation of new phenolic glycolipids from Mycobaclerium tuberculosis

Motoko Watanabe, Yasuji Yamada, Kazuo Iguchi, David E. Minnikin

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1994

Language:

english

File:

PDF, 1010 KB

english, 1994

50

Mycolic acids of representative strains of Nocardia and the ‘rhodochrous’ complex

David E. Minnikin, Pankaj V. Patel, Michael Goodfellow

Journal:

Year:

1974

Language:

english

File:

PDF, 284 KB

english, 1974

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